A three dimensional, stochastic computer model to investigate the biofilm morphology and quorum sensing towards antibiotic susceptibility

DOI: 10.5176/2251-2489_BioTech15.37

Authors: Lakshmi Machineni, Anil Rajapantul, and Parag D. Pawar

Abstract: we present an individual-based 3D computational cellular automata model of a bacterial biofilm developing on a surface in an aqueous environment. The model is used to investigate the roles played by biofilm morphology and QS on its response to antimicrobial agents.

Keywords: Biofilm morphology, Quorum sensing, EPS, Antibiotic treatment