DOI: 10.5176/2382-5685_VETSCI15.37
Authors: Sapikowski Grzegorz, Popiel Jarosław, Nicpoń Józef, *Płoneczka-Janeczko Katarzyna **Dzimira Stanisław and Szczepańska Patrycja
Abstract:
Numerous studies on the biology of stem cells have been carried out in recent years. The obtained results laid the foundations for a new approach in regenerative medicine. To date, autologous tissues have been the main source of stem cells in veterinary medicine. The study was carried out as part of a project that used xenogenic stem cells acquired from the Cervus elaphus deer antlers. The aim of the study was to apply and assess a medical product containing an antlerogenic stem cell homogenate on the mucous membranes, periodontal tissue, skin and nasal plate in dogs. The study was carried out on 12 Faculty kennel beagle dogs. The medical product with and without the antlerogenic stem cell homogenate was applied twice a day for ten days. The clinical, dental and dermatological condition of the dogs and hematological and biochemical blood parameters in venous blood were assessed at two time points. The study demonstrated that the gel containing an antlerogenic stem cell homogenate can be safely used on mucous membranes, periodontal tissue, skin and the nasal plate in dogs. No statistically significant differences in the clinical, dental and dermatological condition of the dogs and blood parameters were found in the course of the study. These results form the basis of future clinical trials using antlerogenic stem cells. This study was conducted as a part of the UOD-DEM-1-352/001 project sponsored by the National Center for Research and Development.
Keywords: antlerogenic stem cells, dogs, regenerative medicine, veterinary stomatology, veterinary dermatology
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