DOI: 10.5176/2251-3833_GHC12.14
Authors: Harikumar Darnal, Karim N, M A J Nur and Afira AS
Abstract: The aim of this preliminary cross sectional study was to find out the prevalence of renal failure in hospital admitted Malaysian diabetic patients. Creatinine clearence (Ccr) was used as endogenous marker of glomerular filtration rate (GFR) for which serum and urine samples were subjected for the assessment. According to the level of Ccr, patients were graded in to acute renal failure (58{6e6090cdd558c53a8bc18225ef4499fead9160abd3419ad4f137e902b483c465}), chronic renal failure (36{6e6090cdd558c53a8bc18225ef4499fead9160abd3419ad4f137e902b483c465}) and diabetic nephropathy (1.5{6e6090cdd558c53a8bc18225ef4499fead9160abd3419ad4f137e902b483c465}). Eighty percent of patients were elderly with age range of 50 to 79 with male dominance of 1.94: 1. Over fifty percent patients (62{6e6090cdd558c53a8bc18225ef4499fead9160abd3419ad4f137e902b483c465}) were obese or overweight. Statistically, basal metabolic rate (BMI) had definite association with severity of diabetic mellitus (p <0.05). Other variables like smoking, high protein diet, urban living and level of education, although statistically not significant, could not be rejected as having no association.Overall our Malaysian diabetic patients have significantly high prevalence of renal failure (94{6e6090cdd558c53a8bc18225ef4499fead9160abd3419ad4f137e902b483c465}) during their hospital stay.
Keywords: Renal failure, diabetic nephropathy, creatinine clearance, metabolic disorder, obesity
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