ISBN: 978-981-08-8407-9
Authors: Lee Seong Wei, Wendy Wee, Marinah Muhammad
Abstract:
This study was conducted to optimize cost and dosage of kanamycin as growth promoter and antimicrobial agent in controlling Edwardsiellosis in Africancatfish (Clarias gariepinus). African catfish were given fish feed in which incorporated with kanamycin at concentration of 4, 8, 16, 32 and 64 mg/kg of fish for 7 days before intraperitonealy (i.p) exposed to Edwardsiella tarda. Survival and daily growth rate of the African catfish were recorded everyday continually until 21 days post-infection. The results of the present study were analysis using response surface method to determine the optimum cost and dosage of kanamycin for the highest survival and daily growth rate of the fish. In the present study, the optimum cost and dosage for 76.5 {6e6090cdd558c53a8bc18225ef4499fead9160abd3419ad4f137e902b483c465} survival rate and 35.3 {6e6090cdd558c53a8bc18225ef4499fead9160abd3419ad4f137e902b483c465} daily growth rate of African catfish was RM 2.00/kg of fish and 10.2 mg/kg of fish, respectively. In term of cost effectiveness, kanamycin showed the potential to be used as antimicrobial agent in aquaculture.
Keywords: Optimization, cost, dosage, kanamycin, survival rate, growth rate, African catfish
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