DOI: 10.5176/978-08-8227-3_BICB2011-27

Authors: Vikram Singh and Ramakrishna Ramaswamy

Abstract:

We analyse symbolic sequences of a large number of known long noncoding genes in a variety of organisms via their Fourier and wavelet transforms. Although these do not have the striking correlation structure of protein coding genes, there are significant patterns within the sequences which can be detected through spectral methods. While these methods are not by themselves of sufficient accuracy to detect noncoding genes, they can provide useful filters to be used in conjunction with other tools for the identification of noncoding genes.

Keywords: ncRNA; coding RNA; Long-range correlations in DNA; Wavelet Transforms; Detrended Fluctuation Analysis; Power Spectrum Analysis.

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