Binding Characteristics of Curcumin to Beta Casein Micelles and its Hydrolysates

DOI: 10.5176/2251-2489_BioTech35

Authors: Seyed Mahmood Ghaffari, Mansoore Esmaili and Ali Akbar Moosavi Movahedi

Abstract: Curcumin is a potent anticancer and antioxidant natural polyphenol poorly soluble in aqueous solutions. Beta-casein (B-CN) is an amphiphilic self-assembling protein that can form micellar nanostructures. In this study we examined the binding properties of curcumin to this protein and its hydrolytic peptides derived by using binding isotherm plots and fluorescence spectroscopy.

Keywords: Beta casein micelle, Curcumin, Binding isotherm, Circular Dichorism (CD)