ISBN: 978-981-08-8407-9
Authors: Lee Seong Wei, Wendy Wee, Marinah Muhammad
Abstract:
This paper described optimization of cost and dosage of Citrus microcarpa extract against Edwardsiellosis in African catfish (Clarias gariepinus) culture. This study was carried out to determine the minimum cost and dosage of furazolidone and C. microcarpa extract for the maximum survival and growth rate of African catfish infected with Edwardsiella tarda. African fish were treated with C. microcarpa extract at dosage of 2, 4 and 8 g/kg of fish for one week before intraperitoneally infected with Edwardsiella tarda. The infected fish were continually treated with medicated feed for the next three weeks. Survival and daily growth rate of the experimental fish were recorded at the end of experiment. Optimization of cost and dosage of C. microcarpa extract based on survival and daily growth rate of the fish were carried out using response surface methodology. In the present study, the optimum cost and dosage of C. microcarpa extract for 100 {6e6090cdd558c53a8bc18225ef4499fead9160abd3419ad4f137e902b483c465} survival rate and 38.6 {6e6090cdd558c53a8bc18225ef4499fead9160abd3419ad4f137e902b483c465} daily growth rate of African catfish were RM 0.05 per kg of fish and 4.8g per kg of fish, respectively. Based on cost and effectiveness of C. microcarpa in controlling Edwardsiellosis in African catfish indicated the huge potential of thisextract as antimicrobial agent as well as growth promoter for aquaculture use.
Keywords: Response surface, optimization, Citrus microcarpa, Edwardsiellosis, African catfish, Clarias gariepinus
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