Amylase and Lipase Inhibitory Effects Of Certain Oxazine Derivatives

DOI: 10.5176/2345-783X_PHARMA17.9

Authors: Mathew George , Lincy Joseph

Abstract:

Purpose of the study was to synthesize 25 new oxazine derivatives, to characterize their structures by spectrophotometrically and to screen newly synthesized compounds for Amylase and Lipase Inhibitory effects. All the synthesized compounds subjected to amylase and lipase inhibitory effects .Among the tested compounds only seven compounds exhibited good amylase inhibitory effect. And only three showed good lipase inhibitory effects. Aim/Objectives: To synthesize 25 oxazine derivatives, to do structural characterization spectrophotometrically and to screen newly synthesized compounds for Amylase and Lipase Inhibitory effects.

Keywords: Amylase, Lipase, Oxazine.